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Table 1 Maximum likelihood analysis of positive selection in DNA-encoding proteins linked to water metabolism and skin structure

From: Natural selection in bats with historical exposure to white-nose syndrome

Gene

Protein

n

n

M0-M3

M1-M2

M7-M8

  

sp.

ind.

LRT

p

ω (prop.)

LRT

p

ω (prop.)

LRT

p

acad10

ACAD10

4

4

19.6

0..495

1.01 (0%)

0.0

1.000

1.36 (13.3%)

1.4

0.877

acp5

TRAP

9

26

191.5

0.001

6.16 (2.0%)

34.4

0.001

6.05 (2.0%)

38.1

0.001

anxa1

ANXA1

9

16

157.4

0.001

8.57 (15.3%)

57.2

0.001

8.03 (15.5%)

59.1

0.001

aqp3

AQP3

8

28

69.7

0.001

9.22 (1.1%)

14.8

0.004

9.19 (1.1%)

17.1

0.001

aqp4

AQP4

3

3

1.3

1.000

1.00 (3.0%)

0.0

1.000

14.87 (2.5%)

0.6

1.000

aqp7

AQP7

3

3

0.1

1.000

1.00 (5.1%)

0.0

1.000

1.00 (0%)

0.0

1.000

aqp9

AQP9

4

4

12.2

0.028

3.19 (15.5%)

4.3

0.292

3.19 (15.5%)

4.6

0.226

bcam

BCAM/Lu

6

8

73.5

0.004

5.81 (5.2%)

10.5

0.025

5.32 (5.8%)

11.1

0.018

ctnnb1

CTNNB1

4

4

0.0

1.000

1.00 (0%)

0.0

1.000

1.00 (0%)

0.0

1.000

fads1

FADS1

3

3

18.0

0.03

13.40 (1.5%)

7.0

0.085

13.46 (1.6%)

7.2

0.081

fgf10

FGF10

5

5

7.7

0.155

1.00 (1.7%)

0.0

1.000

1.00 (1.8%)

0.1

1.000

guca2b

GUCA2B

7

12

29.1

0.001

3.53 (5.1%)

3.6

0.345

3.23 (6.3%)

5.4

0.172

has2

HAS2

4

4

0.0

1.000

1.00 (0%)

0.0

1.000

1.01 (0%)

0.0

1.000

hyal2

HYAL2

5

5

17.8

0.003

1.00 (2.9%)

0.0

1.000

1.00 (2.9%)

0.0

1.000

hyal3

HYAL3

4

4

0.4

1.000

1.00 (8.2%)

0.0

1.000

1.01 (0%)

0.0

1.000

krt8

KRT8

4

4

0.0

1.000

1.00 (0%)

0.0

1.000

1.00 (0%)

0.0

1.000

lrp4

LRP4

4

4

14.1

0.015

52.96 (1.11%)

9.3

0.035

52.95 (1.11%)

10.1

0.021

psen2

PSEN2

3

3

12.98

0.001

11.39 (1.1%)

4.1

0.351

10.95 (1.2%)

3.9

0.226

ptch2

PTCH2

4

4

67.2

0.001

10.75 (0.4%)

9.110

0.035

10.45 (1.2%)

10.7

0.018

pxn

PXN

4

4

6.6

0.225

1.00 (0%)

0.000

1.000

1.00 (0%)

0.0

1.000

sncg

SNCG

3

3

13.2

0.020

84.38 (1.1%)

11.506

0.018

85.32 (1.1%)

11.8

0.016

tgm1

TGM1

5

5

6.7

0.620

1.00 (4.8%)

0.000

1.000

1.00 (0%)

0.0

1.000

tnfsf13

TNFSF13/APRIL

4

4

12.1

0.028

14.26 (0.6%)

3.286

0.370

8.6 (1.1%)

3.1

0.404

  1. The table shows ω values indicating the ratio of non-synonymous to synonymous substitution rates. n = sample size; sp. - species; ind. - individuals; LRT likelihood ratio test statistic, given as Δ2lnL in the nested models compared (M0-M3, M1-M2 and M7-M8); prop. - proportion of sites with ω > 1; and p-values (adjusted for multiple testing with FDR; significant at α = 0.05) for the corresponding tests. Tests indicating signals of natural selection are in bold